ZBrush MatCaps are COOL and applicable for Blender

MatCap (Material Capture), it is just a one time material that captures even the lightings and the shader of a material and apply it directly to your 3D model without needing of lighting setups.

I provided a wallpaper style tutorial,

(Click for full-view)

Pixologic MatCap Library
- http://www.pixologic.com/zbrush/downloadcenter/library/


or watch it for more further info

Using ZBrush MatCaps in Blender from Kernon Dillon on Vimeo.

Source: http://blendernewbies.blogspot.com/2010/05/using-zbrush-matcaps-in-blender.html